Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0313239
PubChem CID
Molecular Formula
C13H8ClN
Molecular Weight
213.667 g/mol
Synonyms/Alias
[4-Chlorobenzo[f]isoquinoline; CBIQ; 32081-28-0; MFCD02179769; SCHEMBL610880; GTPL4152; CHEMBL1372588; DTXSID30464737; HMS3260E20; Tox21_500109; CBIQ; >=98% (HPLC); solid; AKOS017550392; CCG-221413...
InChI Key
SHQLTRRYZVBEMR-UHFFFAOYSA-N
InChI
InChI=1S/C13H8ClN/c14-13-12-6-5-9-3-1-2-4-10(9)11(12)7-8-15-13/h1-8H
IUPAC Name
4-chlorobenzo[f]isoquinoline
CAS Number
32081-28-0

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

23 25 0 0 0 0 0 0 0 0999 V2000
3.3688 -0.1044 0.0424 C 0 0 0 0 0 0 0 0 0 0 0 0
2.7808 -1.3650 -0.0037 C 0 0 0 0 0 0 0 0 0 0 0 0
1.3902 -1.496...

Experimental Data

Activity Data

Target Ion Channel
Cystic fibrosis transmembrane conductance regulator (Chloride channel)
Uniprot Accession Number
Function
Activator
Species
Homo sapiens (Human)
IC50
N/A (Not available)
EC50
EC50: 4000 nM
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.4
Holding Potential
−80 to 80 mV mV
Temperature
Room Temperature
Test Method
Patch-clamping
Test Species
airway epithelial cell

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
15
Rotatable Bonds
0
logP
4.0414
Complexity
64.259
TPSA (Ų)
12.89
H-Bond Donors
0
H-Bond Acceptors
1
Ring Count
3
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